Cat. No.: IBDA-432708
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Online InquiryTarget Information
| Target Name | CD86 |
| Uniprot ID | P42081 |
| Cellular Localization | Membrane. |
| Immunogen | Recombinant fragment corresponding to Human CD86 (N terminal). |
| Function | Receptor involved in the costimulatory signal essential for T-lymphocyte proliferation and interleukin-2 production, by binding CD28 or CTLA-4. May play a critical role in the early events of T-cell activation and costimulation of naive T-cells, such as deciding between immunity and anergy that is made by T-cells within 24 hours after activation. Isoform 2 interferes with the formation of CD86 clusters, and thus acts as a negative regulator of T-cell activation. |
Product Details
| Description | Rabbit polyclonal antibody to CD86 - N-terminal. |
| Host Species | Rabbit |
| Clonality | Polyclonal |
| Purity | Immunogen affinity purified |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Reactivity | Human |
| Immunogen | Recombinant fragment corresponding to Human CD86 (N terminal). |
| Positive Control | Jurkat, Raji, MCF-7, HeLa, DU145, mouse heart, liver and spleen cell extracts. MCF-7 cells. |
| Application | ICC/IF |
Storage & Handling
| Shipping | Shipped at 4 °C. |
| Storage | Short term: 4 °C. Long term: -20 °C |
| Storage Buffer | pH: 7.40 Preservative: 0.02% Sodium Azide Constituent: 49% PBS, 50% Glycerol, 0.87% Sodium Chloride |
| Handling | Avoid freeze-thaw cycles. |