CDK8-IN-6

Cat. No.: IBDI-432294

CDK8-IN-6 (compound 9) is a potent cyclin-dependent kinase 8 (CDK8) inhibitor with an Kd of 13 nM. CDK8-IN-6 shows cytotoxicity for MOLM-13, OCI-AML3, MV4-11, NRK and H9c2 cells with IC50s of 11.2, 7.5, 8.6, 20.5, 12.5-25 µM, respectively. CDK8-IN-6 has the potential for the research of AML-cancer.

Product Details

Target	CDK
Molecular Weight	413.04
SMILES	C[[email protected]@]12C(C3=CC(Cl)=CN=C3)=CC[[email protected]@]1([H])[[email protected]]4([H])CC[[email protected]@]5([H])C[[email protected]](N(C)C)CC[[email protected]]5(C)[[email protected]@]4([H])CC2

Storage & Handling

Shipping	Room temperature in continental US. May vary elsewhere.
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
Regulatory Status	This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use.