Ciglitazone

Cat. No.: IBDI-435989

Ciglitazone is a potent and selective PPARγ agonist (EC50=3 μM). Ciglitazone inhibits proliferation and differentiation of th17 cells. Ciglitazone is a hypoglycemic agent orally active in the obese-hyperglycemic animal models. Ciglitazone induces apoptosis accompanied by activation of p38 MAPK and nuclear translocation of apoptosis inducing factor (AIF) in opossum kidney (OK) renal epithelial cells.

Product Details

Target	PPAR
Molecular Weight	333.45
Appearance	Solid
Synonyms	ADD-3878, U-63287
SMILES	O=C(N1)SC(CC2=CC=C(OCC3(C)CCCCC3)C=C2)C1=O
Purity	98.89%

Storage & Handling

Shipping	Room temperature in continental US. May vary elsewhere.
Storage	Powder: -20°C/3 years; 4°C/2 years In solvent: -80°C/6 months; -20°C/1 month
Regulatory Status	This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use.