Cat. No.: IBDA-431267
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Online InquiryTarget Information
| Target Name | CLEC-2 |
| Uniprot ID | Q9P126 |
| Cellular Localization | Membrane. |
| Immunogen | Recombinant fragment corresponding to Human CLEC-2 aa 50-250. |
| Function | Acts as a receptor for the platelet-aggregating snake venom protein rhodocytin. Rhodocytin binding leads to tyrosine phosphorylation and this promotes the binding of spleen tyrosine kinase (Syk) and initiation of downstream tyrosine phosphorylation events and activation of PLC-gamma-2. Acts as an attachment factor for human immunodeficiency virus type 1 (HIV-1) and facilitates its capture by platelets. |
Product Details
| Description | Mouse monoclonal antibody to CLEC-2. |
| Host Species | Mouse |
| Clonality | Monoclonal |
| Purity | Protein A purified |
| Isotype | IgG1 |
| Conjugation | Unconjugated |
| Reactivity | Human |
| Immunogen | Recombinant fragment corresponding to Human CLEC-2 aa 50-250. |
| Positive Control | Flow Cyt: human peripheral whole blood, human CLEC2 positive thrombocytes |
| Application | Flo |
Storage & Handling
| Shipping | Shipped at 4 °C. |
| Storage | Short term: 4 °C. Long term: -20 °C |
| Storage Buffer | pH: 7.40 Preservative: 0.098% Sodium Azide Constituent: 99% PBS |
| Handling | Avoid freeze-thaw cycles. |