Cat. No.: IBDA-431266
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Online InquiryTarget Information
| Target Name | CLEC-2 |
| Uniprot ID | Q9P126 |
| Cellular Localization | Membrane. |
| Immunogen | Recombinant full length protein corresponding to Human CLEC-2 aa 1 to the C-terminus. |
| Function | Acts as a receptor for the platelet-aggregating snake venom protein rhodocytin. Rhodocytin binding leads to tyrosine phosphorylation and this promotes the binding of spleen tyrosine kinase (Syk) and initiation of downstream tyrosine phosphorylation events and activation of PLC-gamma-2. Acts as an attachment factor for human immunodeficiency virus type 1 (HIV-1) and facilitates its capture by platelets. |
Product Details
| Description | Rabbit polyclonal antibody to CLEC-2. |
| Host Species | Rabbit |
| Clonality | Polyclonal |
| Purity | Immunogen affinity purified |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Reactivity | Human |
| Immunogen | Recombinant full length protein corresponding to Human CLEC-2 aa 1 to the C-terminus. |
| Positive Control | Human liver cancer tissue. |
| Application | IHC-P |
Storage & Handling
| Shipping | Shipped at 4 °C. |
| Storage | Short term: 4 °C. Long term: -20 °C |
| Storage Buffer | pH: 7.4 Preservative: 0.05% Sodium Azide Constituent: 50% Glycerol, 49% PBS |
| Handling | Avoid freeze-thaw cycles. |