Cat. No.: IBDA-431352
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Online InquiryTarget Information
| Target Name | CLEC5A |
| Uniprot ID | Q9NY25 |
| Cellular Localization | Cell membrane. |
| Immunogen | Recombinant fragment within Human CLEC5A aa 1-188. |
| Function | Functions as a positive regulator of osteoclastogenesis. Cell surface receptor that signals via TYROBP. Regulates inflammatory responses. Acts as a key regulator of synovial injury and bone erosion during autoimmune joint inflammation (By similarity). Critical macrophage receptor for dengue virus serotypes 1-4. The binding of dengue virus to CLEC5A triggers signaling through the phosphylation of TYROBP, this interaction does not result in viral entry, but stimulates proinflammatory cytokine release. |
Product Details
| Description | Rabbit polyclonal antibody to CLEC5A. |
| Host Species | Rabbit |
| Clonality | Polyclonal |
| Purity | Immunogen affinity purified |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Reactivity | Human |
| Immunogen | Recombinant fragment within Human CLEC5A aa 1-188. |
| Positive Control | K562 whole cell lysate. |
| Application | WB |
Storage & Handling
| Shipping | Shipped at 4 °C. |
| Storage | Short term: 4 °C. Long term: -20 °C |
| Storage Buffer | pH: 7 Preservative: 0.01% Thimerosal (Merthiolate) Constituent: 79.99% PBS, 20% Glycerol |
| Handling | Avoid freeze-thaw cycles. |