Clitocine

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Cat. No.: IBDI-430035

Clitocine, an adenosine nucleoside analog isolated from mushroom, is a potent and efficacious readthrough agent. Clitocine acts as a suppressor of nonsense mutations and can induce the production of p53 protein in cells harboring p53 nonsense-mutated alleles. Clitocine can induce apoptosis in multidrug-resistant human cancer cells by targeting Mcl-1. Anticancer activity.

Size (Solution): 10 mM * 1 mL in DMSO

Size (Solid + Solvent): 10 mM * 1 mL ready for reconstitution

Size (Solid):

Product Details

Target	Apoptosis \| Bcl-2 Family
Molecular Weight	287.23
Appearance	Solid
SMILES	OC[[email protected]@H]1[[email protected]@H](O)[[email protected]@H](O)[[email protected]](NC2=C([N+]([O-])=O)C(N)=NC=N2)O1
Structure Classification	Alkaloids
Purity	95.88%

Storage & Handling

Shipping	Room temperature in continental US. May vary elsewhere.
Storage	Powder: -20°C/3 years; 4°C/2 years In solvent: -80°C/6 months; -20°C/1 month
Regulatory Status	This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use.

! For research use only, not intended for any clinical use.