CMLD012073

Cat. No.: IBDI-433028

CMLD012073 is an amidino-rocaglates and is a potent eukaryotic initiation factor 4A (eIF4A) inhibitor. CMLD012073 inhibits the growth of NIH/3T3 cells with an IC50 of 10 nM. CMLD012073 inhibits eukaryotic translation initiation by modifying the behavior of the RNA helicase (eIF4A).

Product Details

Target	Eukaryotic Initiation Factor (eIF)
Molecular Weight	530.57
SMILES	CC1=N[[email protected]@]2(O)[[email protected]](C(OC)=O)[[email protected]@H](C3=CC=CC=C3)[[email protected]]4(C5=CC=C(OC)C=C5)OC6=C(C(OC)=CC(OC)=C6)[[email protected]@]42N1

Storage & Handling

Shipping	Room temperature in continental US. May vary elsewhere.
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
Regulatory Status	This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use.