Complement C3/C3b Monoclonal Antibody

Target Information

Target Name	Complement C3/C3b
Synonyms	Breast Epithelial Mucin | BEM
Immunogen	Native human C3 / Complement C3.

Product Details

Description	C3b antibody is an unconjugated mouse monoclonal antibody to human C3b (Complement C3).
Host Species	Mouse
Clonality	Monoclonal
Purity	Protein A purified
Conjugation	Unconjugated
Modifications	Unmodified
Reactivity	Human
Specificity	Recognizes human C3b, part of the complement system. C3 is cleaved by C3-convertase creating C3a and C3b, which binds to the surface of pathogens leading to their destruction by phagocytic cells. Recognizes a determinant present on native (circulating) C3 and on the fragments C3b and C3c. The antibody is directed to a determinant present on the beta chain of the C3 molecule (Western blot). It does not react with the anaphylatoxin C3a or the fragment C3d and does not inhibit the hemolytic function of C3.
Immunogen	Native human C3 / Complement C3.
Application	IHC-Fr, WB

Storage & Handling

Shipping	Shipped at 4 °C.
Storage	Prior to reconstitution, 4 °C. Following reconstitution store at -20 °C
Storage Buffer	PBS, 0.09% Sodium Azide, 0.5% BSA
Handling	Avoid freeze-thaw cycles.