COX-2-IN-10

Cat. No.: IBDI-432577

COX-2-IN-10 is a potent COX-2 inhibitor. COX-2-IN-10 inhibits the production of PGE2 in concentration dependent manner (IC50=2.54 µM). COX-2-IN-10 inhibits the expression of iNOS and COX-2 on mRNA and protein level . COX-2-IN-10 inhibits the production of IL-6, TNF-α and IL-1β.

Product Details

Target	COX
Molecular Weight	557.68
SMILES	CC(C)(N1C=C(C(C2=CC(F)=CC=C2)=N1)C3=CC=NC(NCCCNS(=O)(C4=CC5=C(C=C4)C=CC=C5)=O)=C3)C

Storage & Handling

Shipping	Room temperature in continental US. May vary elsewhere.
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
Regulatory Status	This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use.