Cat. No.: IBDA-433730
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Online InquiryTarget Information
Target Name | CREB |
Uniprot ID | P16220 |
Cellular Localization | Nucleus. |
Immunogen | Synthetic peptide within Human CREB aa 250-350. |
Function | This protein binds the cAMP response element (CRE), a sequence present in many viral and cellular promoters. CREB stimulates transcription on binding to the CRE. Transcription activation is enhanced by the TORC coactivators which act independently of Ser-133 phosphorylation. Implicated in synchronization of circadian rhythmicity. |
Product Details
Description | Rabbit monoclonal antibody to CREB. |
Host Species | Rabbit |
Clonality | Monoclonal |
Purity | Protein A purified |
Isotype | IgG |
Conjugation | Unconjugated |
Reactivity | Mouse, Rat, Human |
Immunogen | Synthetic peptide within Human CREB aa 250-350. |
Positive Control | ICC/IF: PC 12 cells. WB: A431 cell lysate. IHC-P: Prostatic carcinoma tissue. |
Application | IHC-P, WB |
Storage & Handling
Shipping | Shipped at 4 °C. |
Storage | Short term: 4 °C. Long term: -20 °C |
Storage Buffer | pH: 7.20 Preservative: 0.01% Sodium Azide Constituent: 49% PBS, 50% Glycerol, 0.05% BSA |
Handling | Avoid freeze-thaw cycles. |