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CREB Monoclonal Antibody

Cat. No.: IBDA-433732

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Target Information

Target Name CREB
Uniprot ID P16220
Cellular Localization Nucleus.
Immunogen Recombinant full length protein corresponding to Human CREB aa 1-341.
Function This protein binds the cAMP response element (CRE), a sequence present in many viral and cellular promoters. CREB stimulates transcription on binding to the CRE. Transcription activation is enhanced by the TORC coactivators which act independently of Ser-133 phosphorylation. Implicated in synchronization of circadian rhythmicity.

Product Details

Description Mouse monoclonal antibody to CREB.
Host Species Mouse
Clonality Monoclonal
Purity Protein A purified
Isotype IgG1
Conjugation Unconjugated
Reactivity Mouse, Rat, Human, African green monkey
Immunogen Recombinant full length protein corresponding to Human CREB aa 1-341.
Positive Control HeLa cells. Human bladder and rectal cancer tissues. Human tonsil tissue. Human Jurkat, NIH/3T3, C2C12, MDA-MB-231, T98G, HeLa, 293T, HepG2, A431, A549, K562, MCF7 and U2OS whole cell lysates. Mouse MEF, 3T3L1 and C2C12 whole cell lyastes. Rat NRK whole cell lysate. Monkey COS7 whole cell lysate.
Application ICC/IF, IHC-P, IP, WB

Storage & Handling

Shipping Shipped at 4 °C.
Storage Short term: 4 °C. Long term: -20 °C
Storage Buffer Preservative: 0.05% Sodium Azide
Constituent: 0.1% BSA, 99% PBS
Handling Avoid freeze-thaw cycles.
! For research use only, not intended for any clinical use.