Cat. No.: IBDA-433732
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Online InquiryTarget Information
Target Name | CREB |
Uniprot ID | P16220 |
Cellular Localization | Nucleus. |
Immunogen | Recombinant full length protein corresponding to Human CREB aa 1-341. |
Function | This protein binds the cAMP response element (CRE), a sequence present in many viral and cellular promoters. CREB stimulates transcription on binding to the CRE. Transcription activation is enhanced by the TORC coactivators which act independently of Ser-133 phosphorylation. Implicated in synchronization of circadian rhythmicity. |
Product Details
Description | Mouse monoclonal antibody to CREB. |
Host Species | Mouse |
Clonality | Monoclonal |
Purity | Protein A purified |
Isotype | IgG1 |
Conjugation | Unconjugated |
Reactivity | Mouse, Rat, Human, African green monkey |
Immunogen | Recombinant full length protein corresponding to Human CREB aa 1-341. |
Positive Control | HeLa cells. Human bladder and rectal cancer tissues. Human tonsil tissue. Human Jurkat, NIH/3T3, C2C12, MDA-MB-231, T98G, HeLa, 293T, HepG2, A431, A549, K562, MCF7 and U2OS whole cell lysates. Mouse MEF, 3T3L1 and C2C12 whole cell lyastes. Rat NRK whole cell lysate. Monkey COS7 whole cell lysate. |
Application | ICC/IF, IHC-P, IP, WB |
Storage & Handling
Shipping | Shipped at 4 °C. |
Storage | Short term: 4 °C. Long term: -20 °C |
Storage Buffer | Preservative: 0.05% Sodium Azide Constituent: 0.1% BSA, 99% PBS |
Handling | Avoid freeze-thaw cycles. |