Cat. No.: IBDA-433724
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Online InquiryTarget Information
| Target Name | CREB (phospho S129 + S133) |
| Uniprot ID | P16220 |
| Cellular Localization | Nucleus. |
| Immunogen | Synthetic peptide corresponding to Human CREB (phospho S129 + S133). |
| Function | This protein binds the cAMP response element (CRE), a sequence present in many viral and cellular promoters. CREB stimulates transcription on binding to the CRE. Transcription activation is enhanced by the TORC coactivators which act independently of Ser-133 phosphorylation. Implicated in synchronization of circadian rhythmicity. |
Product Details
| Description | Rabbit polyclonal antibody to CREB (phospho S129 + S133). |
| Host Species | Rabbit |
| Clonality | Polyclonal |
| Purity | Immunogen affinity purified |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Reactivity | Mouse, Human |
| Immunogen | Synthetic peptide corresponding to Human CREB (phospho S129 + S133). |
| Positive Control | WB: NIH3T3 cell extract with various treatments. A549 cell extract with various treatments. NIH3T3, A549, SK-N-SH, MCF7, and MDA-MB-231 untreated, EGF-treated or PDGF-treated cell lysates. ICC/IF: 70% confluent log phase HeLa cells. |
| Application | ICC/IF, WB |
Storage & Handling
| Shipping | Shipped at 4 °C. |
| Storage | Upon delivery aliquot. Store at -20 °C or -80 °C |
| Storage Buffer | pH: 7.3 Preservative: 0.05% Sodium Azide Constituent: PBS, 50% Glycerol, 0.1% BSA |
| Handling | Avoid freeze-thaw cycles. |