Cat. No.: IBDA-433731
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Online InquiryTarget Information
| Target Name | CREB (phospho S133) |
| Uniprot ID | P16220 |
| Cellular Localization | Nucleus. |
| Immunogen | Synthetic peptide. |
| Function | This protein binds the cAMP response element (CRE), a sequence present in many viral and cellular promoters. CREB stimulates transcription on binding to the CRE. Transcription activation is enhanced by the TORC coactivators which act independently of Ser-133 phosphorylation. Implicated in synchronization of circadian rhythmicity. |
Product Details
| Description | Rabbit monoclonal antibody to CREB (phospho S133). |
| Host Species | Rabbit |
| Clonality | Monoclonal |
| Purity | Protein A purified |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Reactivity | Mouse, Rat, Human |
| Immunogen | Synthetic peptide. |
| Positive Control | WB: A431 cell lysate. HeLa treated with anisomycin for 30 minutes ICC/IF: A431 and HeLa IHC-P: Human thyroid gland adenocarcinoma, human astrocytoma, rat cereburm and mouse cerebrum tissues. IP: HeLa treated with 25 ug/mL anisomycin for 30 minutes. |
| Application | Flo, ICC/IF, IHC-P, IP, WB |
Storage & Handling
| Shipping | Shipped at 4 °C. |
| Storage | Short term: 4 °C. Long term: -20 °C |
| Storage Buffer | pH: 7.20 Preservative: 0.01% Sodium Azide Constituent: 59% PBS, 40% Glycerol, 0.05% BSA |
| Handling | Avoid freeze-thaw cycles. |