Cat. No.: IBDA-435297
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Online InquiryTarget Information
| Target Name | CXCL11 |
| Uniprot ID | O14625 |
| Cellular Localization | Secreted. |
| Immunogen | Recombinant fragment. |
| Function | Chemotactic for interleukin-activated T-cells but not unstimulated T-cells, neutrophils or monocytes. Induces calcium release in activated T-cells. Binds to CXCR3. May play an important role in CNS diseases which involve T-cell recruitment. May play a role in skin immune responses. |
Product Details
| Description | Rabbit monoclonal antibody to CXCL11. |
| Host Species | Rabbit |
| Clonality | Monoclonal |
| Purity | Protein A purified |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Reactivity | Human |
| Immunogen | Recombinant fragment. |
| Positive Control | WB: Human CXCL11 recombinant protein (aa22-94). THP-1 treated with 200 ng/ml interferon-gamma and 50 ng/ml lipopolysaccharide (LPS) for 24 hours, followed by 300 ng/ml Brefeldin A (BFA) for 20 hours, whole cell lysate. IP: THP-1 treated with 200 ng/ml interferon-gamma and 50 ng/ml lipopolysaccharide (LPS) for 24 hours, followed by 300 ng/ml Brefeldin A (BFA) for 20 hours, whole cell lysate. |
| Application | IP, WB |
Storage & Handling
| Shipping | Shipped at 4 °C. |
| Storage | Short term: 4 °C. Long term: -20 °C |
| Storage Buffer | pH: 7.2 Preservative: 0.01% Sodium Azide Constituent: PBS, 40% Glycerol, 0.05% BSA |
| Handling | Avoid freeze-thaw cycles. |