CXCL7/PBP Monoclonal Antibody

Target Information

Target Name	CXCL7/PBP
Uniprot ID	P02775
Cellular Localization	Secreted.
Immunogen	Recombinant full length protein.
Function	LA-PF4 stimulates DNA synthesis, mitosis, glycolysis, intracellular cAMP accumulation, prostaglandin E2 secretion, and synthesis of hyaluronic acid and sulfated glycosaminoglycan. It also stimulates the formation and secretion of plasminogen activator by human synovial cells. NAP-2 is a ligand for CXCR1 and CXCR2, and NAP-2, NAP-2(73), NAP-2(74), NAP-2(1-66), and most potent NAP-2(1-63) are chemoattractants and activators for neutrophils. TC-1 and TC-2 are antibacterial proteins, in vitro released from activated platelet alpha-granules. CTAP-III(1-81) is more potent than CTAP-III desensitize chemokine-induced neutrophil activation.

Product Details

Description	Rabbit monoclonal antibody to CXCL7/PBP.
Host Species	Rabbit
Clonality	Monoclonal
Purity	Protein A purified
Isotype	IgG
Conjugation	Unconjugated
Reactivity	Mouse
Immunogen	Recombinant full length protein.
Positive Control	WB: Mouse CXCL7/PBP active protein. Mouse spleen, platelet, plasma and serum lysates. IHC-P: Mouse spleen and lung tissues. IHC-Fr: Mouse spleen tissue. IP: Mouse spleen lysate.
Application	IHC-Fr, IHC-P, IP, WB

Storage & Handling

Shipping	Shipped at 4 °C.
Storage	Short term: 4 °C. Long term: -20 °C
Storage Buffer	pH: 7.2 Preservative: 0.01% Sodium Azide Constituent: 59% PBS, 40% Glycerol, 0.05% BSA
Handling	Avoid freeze-thaw cycles.