Cyclovirobuxine D

Cat. No.: IBDI-430001

Cyclovirobuxine D (CVB-D) is the main active component of the traditional Chinese medicine Buxus microphylla. Cyclovirobuxine D induces autophagy and attenuates the phosphorylation of Akt and mTOR. Cyclovirobuxine D inhibits cell proliferation of gastric cancer cells through suppression of cell cycle progression and inducement of mitochondria-mediated apoptosis. Cyclovirobuxine D is beneficial for heart failure induced by myocardial infarction.

Product Details

Target	Apoptosis | Autophagy | mTOR | Akt
Molecular Weight	402.66
Appearance	Solid
SMILES	C[[email protected]](NC)[[email protected]@]1([H])[[email protected]](O)C[[email protected]@]2(C)[[email protected]]3([H])CC[[email protected]@]4([H])C(C)(C)[[email protected]@H](NC)CC[[email protected]]4(C5)[[email protected]]35CC[[email protected]@]21C
Structure Classification	Alkaloids
Purity	≥98.0%

Storage & Handling

Shipping	Room temperature in continental US. May vary elsewhere.
Storage	Powder: -20°C/3 years; 4°C/2 years In solvent: -80°C/6 months; -20°C/1 month
Regulatory Status	This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use.