Cytochalasin D
Cat. No.: IBDI-430539
Cytochalasin D (Zygosporin A) is a potent actin polymerization inhibitor, could be derived from fungus. Cytochalasin D has cell-permeable activity. Cytochalasin D inhibits the G-actin–cofilin interaction by binding to G-actin. Cytochalasin D also inhibits the binding of cofilin to F-actin and decreases the rate of both actin polymerization and depolymerization in living cells. Cytochalasin D can reduce exosome release, in turn reducing the amount of survivin present in the tumour environment. Cytochalasin D induces phosphorylation and cytoplasmic retention of Yap.
Size (Solid + Solvent): 10 mM * 1 mL ready for reconstitution
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Product Details
| Target |
Arp2/3 Complex | Antibiotic | YAP |
| Molecular Weight |
507.62 |
| Appearance |
Solid |
| Synonyms |
Zygosporin A, NSC 209835 |
| Structure Classification |
Others |
| Purity |
99.82% |
Storage & Handling
| Shipping |
Room temperature in continental US. May vary elsewhere. |
| Storage |
Powder: -20°C/3 years
In solvent: -80°C/6 months; -20°C/1 month |
| Regulatory Status |
This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. |
! For research use only, not intended for any clinical use.
