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DC1SMe

Cat. No.: IBDI-435044

DC1Sme, a DC1 derivative, exhibits IC50 values of 22 pM, 10 pM, 32 pM and 250 pM for Ramos, Namalwa, HL60/s and COLO 205 cancer cells, respectively. DC1, an analogue of the minor groove-binding DNA alkylator CC-1065, is a ADC Cytotoxin. DC1 can be used in synthesis of antibody-drug conjugates for the targeted treatment of cancer.

Size (Solution): 10 mM * 1 mL in DMSO

Size (Solid):

Product Details

Target ADC Cytotoxin
Molecular Weight 684.23
Appearance Solid
SMILES O=C(C(N1)=CC2=C1C=CC(NC(CCSSC)=O)=C2)NC3=CC4=C(NC(C(N5C[[email protected]@H](CCl)C6=C5C=C(O)C7=CC=CC=C67)=O)=C4)C=C3
Purity ≥98.0%

Storage & Handling

Shipping Room temperature in continental US. May vary elsewhere.
Storage Please store the product under the recommended conditions in the Certificate of Analysis.
Regulatory Status This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use.
! For research use only, not intended for any clinical use.
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