Debio 0617B

Cat. No.: IBDI-435650

Debio 0617B, a multi-kinase inhibitor, reduces maintenance and self-renewal of primary human AML CD34 + stem/progenitor cells. Debio 0617B has a unique profile targeting key kinases upstream of STAT3/STAT5 signaling such as JAK, SRC, ABL, and class III/V receptor tyrosine kinases (TKs). Debio 0617B has documented efficacy in STAT3-driven solid tumors.

Product Details

Target	STAT | JAK | Bcr-Abl
Molecular Weight	581.98
SMILES	O=C(C1=NC=CC(C(F)(F)F)=C1)NC2=CC=C(Cl)C(N3CCC4=NC(NC5=CC=C(C(NC)=O)C=C5)=NC=C4C3)=C2

Storage & Handling

Shipping	Room temperature in continental US. May vary elsewhere.
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
Regulatory Status	This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use.