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Decitabine

Cat. No.: IBDI-434758

Decitabine (NSC 127716) is an orally active deoxycytidine analogue antimetabolite and a DNA methyltransferase inhibitor. Decitabine incorporates into DNA in place of cytosine can covalently trap DNA methyltransferase to DNA causing irreversible inhibition of the enzyme. Decitabine induces cell G2/M arrest and cell apoptosis. Decitabine has potent anticancer activity.

Size (Solution): 10 mM * 1 mL in DMSO

Size (Solid + Solvent): 10 mM * 1 mL ready for reconstitution

Size (Solid):

Product Details

Target DNA MethyltransfeRase | Apoptosis | Nucleoside Antimetabolite/Analog
Molecular Weight 228.21
Appearance Solid
Synonyms 5-Aza-2'-deoxycytidine, 5-AZA-CdR, NSC 127716
SMILES O[[email protected]]1C[[email protected]](N2C(N=C(N)N=C2)=O)O[[email protected]@H]1CO

Storage & Handling

Shipping Room temperature in continental US. May vary elsewhere.
Storage Please store the product under the recommended conditions in the Certificate of Analysis.
Regulatory Status This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use.
! For research use only, not intended for any clinical use.
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