Dectin-1 Monoclonal Antibody

Target Information

Target Name	Dectin-1
Uniprot ID	Q9BXN2
Cellular Localization	Cytoplasm and Cell membrane.
Immunogen	Tissue, cells or virus corresponding to Human Dectin-1.
Function	Lectin that functions as pattern receptor specific for beta-1,3-linked and beta-1,6-linked glucans, such as cell wall constituents from pathogenic bacteria and fungi. Necessary for the TLR2-mediated inflammatory response and for TLR2-mediated activation of NF-kappa-B. Enhances cytokine production in macrophages and dendritic cells. Mediates production of reactive oxygen species in the cell. Mediates phagocytosis of C.albicans conidia. Binds T-cells in a way that does not involve their surface glycans and plays a role in T-cell activation. Stimulates T-cell proliferation.

Product Details

Description	Mouse monoclonal antibody to Dectin-1 - Low Endotoxin, Azide Free.
Host Species	Mouse
Clonality	Monoclonal
Purity	Protein G purified
Isotype	IgG1
Conjugation	Unconjugated
Reactivity	Human
Immunogen	Tissue, cells or virus corresponding to Human Dectin-1.
Positive Control	Human peripheral blood monocytes
Application	Flo, Inhibition

Storage & Handling

Shipping	Shipped at 4 °C.
Storage	Upon delivery aliquot. Store at -20 °C or -80 °C
Storage Buffer	pH: 7.40 Constituent: PBS
Handling	Avoid freeze-thaw cycles.