Cat. No.: IBDA-431510
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Online InquiryTarget Information
| Target Name | Dectin-1 |
| Uniprot ID | Q9BXN2 |
| Cellular Localization | Cytoplasm and Cell membrane. |
| Immunogen | This product was produced with the following immunogens:Recombinant full length protein corresponding to Dectin-1. |
| Function | Lectin that functions as pattern receptor specific for beta-1,3-linked and beta-1,6-linked glucans, such as cell wall constituents from pathogenic bacteria and fungi. Necessary for the TLR2-mediated inflammatory response and for TLR2-mediated activation of NF-kappa-B. Enhances cytokine production in macrophages and dendritic cells. Mediates production of reactive oxygen species in the cell. Mediates phagocytosis of C.albicans conidia. Binds T-cells in a way that does not involve their surface glycans and plays a role in T-cell activation. Stimulates T-cell proliferation. |
Product Details
| Description | Rat monoclonal antibody to Dectin-1. |
| Host Species | Rat |
| Clonality | Monoclonal |
| Purity | Protein G purified |
| Isotype | IgG2b |
| Conjugation | Unconjugated |
| Reactivity | Mouse |
| Immunogen | This product was produced with the following immunogens:Recombinant full length protein corresponding to Dectin-1. |
| Application | Flo |
Storage & Handling
| Shipping | Shipped at 4 °C. |
| Storage | Short term: 4 °C. Long term: -20 °C |
| Storage Buffer | pH: 7.40 Preservative: 0.09% Sodium Azide Constituent: PBS |
| Handling | Avoid freeze-thaw cycles. |