Dectin-1 Polyclonal Antibody

Target Information

Target Name	Dectin-1
Uniprot ID	Q9BXN2
Cellular Localization	Cytoplasm and Cell membrane.
Immunogen	Synthetic peptide within Human Dectin-1 aa 70-120 (extracellular).
Function	Lectin that functions as pattern receptor specific for beta-1,3-linked and beta-1,6-linked glucans, such as cell wall constituents from pathogenic bacteria and fungi. Necessary for the TLR2-mediated inflammatory response and for TLR2-mediated activation of NF-kappa-B. Enhances cytokine production in macrophages and dendritic cells. Mediates production of reactive oxygen species in the cell. Mediates phagocytosis of C.albicans conidia. Binds T-cells in a way that does not involve their surface glycans and plays a role in T-cell activation. Stimulates T-cell proliferation.

Product Details

Description	Rabbit polyclonal antibody to Dectin-1.
Host Species	Rabbit
Clonality	Polyclonal
Purity	Immunogen affinity purified
Isotype	IgG
Conjugation	Unconjugated
Reactivity	Rat, Human
Immunogen	Synthetic peptide within Human Dectin-1 aa 70-120 (extracellular).
Positive Control	WB: Rat spleen tissue lysate IHC-P: Human spleen tissue ICC/IF: Jurkat cells
Application	ICC/IF, IHC-P, WB

Storage & Handling

Shipping	Shipped at 4 °C.
Storage	Short term: 4 °C. Long term: -20 °C
Storage Buffer	pH: 7.2 Preservative: 0.02% Sodium Azide Constituent: 99% PBS
Handling	Avoid freeze-thaw cycles.