Cat. No.: IBDA-431773
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Online InquiryTarget Information
| Target Name | DECTIN 2 |
| Uniprot ID | Q6EIG7 |
| Cellular Localization | Membrane. |
| Immunogen | Recombinant fragment corresponding to Mouse DECTIN 2 aa 44-209 (extracellular). |
| Function | Binds high-mannose carbohydrates in a Ca(2+)-dependent manner. Functional receptor for alpha-mannans on C.albicans hypheas. Plays an important role in the host defense against C.albicans infection by inducing TH17 cell differentiation. Recognizes also, in a mannose-dependent manner, allergens from house dust mite and fungi, by promoting cysteinyl leukotriene production. Recognizes soluble elements from the eggs of Shistosoma mansoni altering adaptive immune responses. Transduces signals through an Fc receptor gamma chain /FCER1G and Syk-CARD9-NF-kappa-B-dependent pathway. |
Product Details
| Description | Rat monoclonal antibody to DECTIN 2. |
| Host Species | Rat |
| Clonality | Monoclonal |
| Purity | Protein G purified |
| Isotype | IgG2a |
| Conjugation | Unconjugated |
| Reactivity | Mouse |
| Immunogen | Recombinant fragment corresponding to Mouse DECTIN 2 aa 44-209 (extracellular). |
| Positive Control | IHC-P: Mouse spleen tissue. |
| Application | IHC-Fr |
Storage & Handling
| Shipping | Shipped at 4 °C. |
| Storage | Short term: 4 °C. Long term: -20 °C |
| Storage Buffer | Preservative: 0.09% Sodium Azide Constituent: 99% PBS |
| Handling | Avoid freeze-thaw cycles. |