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DHFR-IN-4

Cat. No.: IBDI-435616

DHFR-IN-4 is a potent dihydrofolate reductase (DHFR) inhibitor with an IC50 value of 123 nM. DHFR-IN-4 also has inhibitory activity against EGFR and HER2 with IC50s of 246 nM and 357 nM, respectively. DHFR-IN-4 has remarkable broad spectrum cytotoxic potency against cancer cells.

Size (Solid):

Product Details

Target Dihydrofolate reductase (DHFR) | EGFR
Molecular Weight 371.46
SMILES O=C(C1=CSC2=NC(CN3CCOCC3)=C(C4=CC=C(C)C=C4)N21)NN

Storage & Handling

Shipping Room temperature in continental US. May vary elsewhere.
Storage Please store the product under the recommended conditions in the Certificate of Analysis.
Regulatory Status This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use.
! For research use only, not intended for any clinical use.