Diprovocim

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Cat. No.: IBDI-436025

Diprovocim is a potent TLR1/TLR2 agonist. Diprovocim elicits full agonist activity in human THP-1 cells (EC50=110 pM). Diprovocim stimulates the release of TNF-α from mouse macrophages (EC50=1.3 nM). Diprovocim activates downstream MAPK and NF-κB signaling pathway. Diprovocim displays strong adjuvant activity in mice, particularly abetting cellular immune responses.

Size (Solid):

Product Details

Target	Toll-like Receptor (TLR) \| TNF Receptor \| p38 MAPK \| NF-κB
Molecular Weight	909.08
Appearance	Solid
SMILES	O=C(N1C[[email protected]@H](C(N[[email protected]@H]2[[email protected]@H](C3=CC=CC=C3)C2)=O)[[email protected]](C(N[[email protected]@H]4[[email protected]@H](C5=CC=CC=C5)C4)=O)C1)C6=CC=C(C(N7C[[email protected]@H](C(N[[email protected]@H]8[[email protected]@H](C9=CC=CC=C9)C8)=O)[[email protected]](C(N[[email protected]@H]%10[[email protected]@H](C%11=CC=CC=C%11)C%10)=O)C7)=O)C=C6
Purity	98.35%

Storage & Handling

Shipping	Room temperature in continental US. May vary elsewhere.
Storage	Powder: -20°C/3 years; 4°C/2 years In solvent: -80°C/6 months; -20°C/1 month
Regulatory Status	This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use.

! For research use only, not intended for any clinical use.