Disulfiram
Cat. No.: IBDI-438204
Disulfiram (Tetraethylthiuram disulfide) is a specific inhibitor of aldehyde-dehydrogenase (ALDH1), used for the treatment of chronic alcoholism by producing an acute sensitivity to alcohol. Disulfiram inhibits gasdermin D (GSDMD) pore formation in liposomes and inflammasome-mediated pyroptosis and IL-1β secretion in human and mouse cells. Disulfiram + Cu 2+ increases intracellular ROS levels triggering apoptosis of ovarian cancer stem cells.
Size (Solid + Solvent): 10 mM * 1 mL ready for reconstitution
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Product Details
| Target |
Aldehyde Dehydrogenase (ALDH) | Interleukin Related | Pyroptosis | Apoptosis |
| Molecular Weight |
296.54 |
| Appearance |
Solid |
| Synonyms |
Tetraethylthiuram disulfide, TETD |
| Purity |
99.78% |
Storage & Handling
| Shipping |
Room temperature in continental US. May vary elsewhere. |
| Storage |
Powder: -20°C/3 years; 4°C/2 years
In solvent: -80°C/6 months; -20°C/1 month |
| Regulatory Status |
This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. |
! For research use only, not intended for any clinical use.
