Docetaxel-d5 trihydrate

Cat. No.: IBDI-436801

Docetaxel-d5 (trihydrate) is the deuterium labeled Docetaxel (Trihydrate). Docetaxel Trihydrate (RP-56976 Trihydrate) is an antineoplastic agent and inhibits microtubule depolymerization with an IC50 value of 0.2 μM. Docetaxel Trihydrate is a semisynthetic analog of taxol and attenuates the effects of bcl-2 and bcl-xL gene expression. Docetaxel Trihydrate arrests the cell cycle at G2/M and leads to cell apoptosis.

Product Details

Target	Microtubule/Tubulin | Apoptosis
Molecular Weight	866.96
SMILES	O=C(OC(C)(C)C)N[[email protected]]([[email protected]](C(O[[email protected]@H]1C(C)=C([[email protected]@H](O)C([[email protected]@]2(C)[[email protected]]([[email protected]@](CO3)(OC(C)=O)[[email protected]@]3([H])C[[email protected]@H]2O)([H])[[email protected]@H]4OC(C5=C([2H])C([2H])=C([2H])C([2H])=C5[2H])=O)=O)C(C)(C)[[email protected]@]4(O)C1)=O)O)C6=CC=CC=C6.O.O.O

Storage & Handling

Shipping	Room temperature in continental US. May vary elsewhere.
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
Regulatory Status	This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use.