Docetaxel-d9

Cat. No.: IBDI-432756

Docetaxel-d9 is the deuterium labeled Docetaxel. Docetaxel (RP-56976) is a microtubule depolymerization inhibitor, with an IC50 of 0.2 μM. Docetaxel attenuates the effects of bcl-2 and bcl-xL gene expression. Docetaxel arrests the cell cycle at G2/M and leads to cell apoptosis. Docetaxel has anti-cancer activity.

Product Details

Target	Microtubule/Tubulin | Apoptosis | Endogenous Metabolite
Molecular Weight	816.93
Appearance	Solid
Synonyms	RP-56976-d9
SMILES	CC(O[[email protected]]12[[email protected]@]3([H])[[email protected]@H]([[email protected]]4(C(C)(C([[email protected]](C([[email protected]@]3([[email protected]](C[[email protected]@]1([H])OC2)O)C)=O)O)=C([[email protected]](C4)OC([[email protected]](O)[[email protected]](C5=CC=CC=C5)NC(OC(C([2H])([2H])[2H])(C([2H])([2H])[2H])C([2H])([2H])[2H])=O)=O)C)C)O)OC(C6=CC=CC=C6)=O)=O

Storage & Handling

Shipping	Room temperature in continental US. May vary elsewhere.
Storage	Powder: -20°C/3 years; 4°C/2 years In solvent: -80°C/6 months; -20°C/1 month
Regulatory Status	This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use.