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* Please note that all of our services and products are intended for preclinical research use only and cannot be used to diagnose, treat or manage patients.

Docetaxel

Cat. No.: IBDI-436799

Docetaxel (RP-56976) is a microtubule depolymerization inhibitor, with an IC50 of 0.2 μM. Docetaxel attenuates the effects of bcl-2 and bcl-xL gene expression. Docetaxel arrests the cell cycle at G2/M and leads to cell apoptosis. Docetaxel has anti-cancer activity.

Size (Solution): 10 mM * 1 mL in DMSO

Size (Solid + Solvent): 10 mM * 1 mL ready for reconstitution

Size (Solid):

Product Details

Target Microtubule/Tubulin | Apoptosis | Endogenous Metabolite
Molecular Weight 807.88
Appearance Solid
Synonyms RP-56976
SMILES O=C(OC(C)(C)C)N[[email protected]@H](C1=CC=CC=C1)[[email protected]](C(O[[email protected]@H]2C(C)=C([[email protected]@H](O)C([[email protected]@]3(C)[[email protected]]([[email protected]@](CO4)(OC(C)=O)[[email protected]@]4([H])C[[email protected]@H]3O)([H])[[email protected]@H]5OC(C6=CC=CC=C6)=O)=O)C(C)(C)[[email protected]@]5(O)C2)=O)O
Purity 99.42%

Storage & Handling

Shipping Room temperature in continental US. May vary elsewhere.
Storage Please store the product under the recommended conditions in the Certificate of Analysis.
Regulatory Status This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use.
! For research use only, not intended for any clinical use.