Docetaxel Trihydrate

Cat. No.: IBDI-436800

Docetaxel Trihydrate (RP-56976 Trihydrate) is an antineoplastic agent and inhibits microtubule depolymerization with an IC50 value of 0.2 μM. Docetaxel Trihydrate is a semisynthetic analog of taxol and attenuates the effects of bcl-2 and bcl-xL gene expression. Docetaxel Trihydrate arrests the cell cycle at G2/M and leads to cell apoptosis.

Product Details

Target	Microtubule/Tubulin | Apoptosis
Molecular Weight	861.93
Appearance	Solid
Synonyms	RP-56976 Trihydrate
SMILES	O=C(OC(C)(C)C)N[[email protected]]([[email protected]](C(O[[email protected]@H]1C(C)=C([[email protected]@H](O)C([[email protected]@]2(C)[[email protected]]([[email protected]@](CO3)(OC(C)=O)[[email protected]@]3([H])C[[email protected]@H]2O)([H])[[email protected]@H]4OC(C5=CC=CC=C5)=O)=O)C(C)(C)[[email protected]@]4(O)C1)=O)O)C6=CC=CC=C6.O.O.O
Purity	99.92%

Storage & Handling

Shipping	Room temperature in continental US. May vary elsewhere.
Storage	Powder: -20°C/3 years; 4°C/2 years In solvent: -80°C/6 months; -20°C/1 month
Regulatory Status	This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use.