Echinomycin

Cat. No.: IBDI-431901

Echinomycin (Quinomycin A) is potent small-molecule and cell-permeable inhibitor of hypoxia-inducible factor-1 (HIF-1) DNA-binding activity. Echinomycin selectively inhibits the cancer stem cells (CSCs) with an IC50 of 29.4 pM.

Product Details

Target	HIF/HIF Prolyl-Hydroxylase | Antibiotic | Bacterial
Molecular Weight	1101.26
Appearance	Solid
Synonyms	Quinomycin A, NSC-13502
SMILES	[H]C1=NC2=C(N=C1C(N[[email protected]](COC([[email protected]](C(C)C)N(C)C([[email protected]]3N4C)=O)=O)C(N[[email protected]@H](C)C(N(C)[[email protected]@H]([[email protected]@H](SC)SC3)C(N(C)[[email protected]@H](C(C)C)C(OC[[email protected]@H](NC(C5=NC6=C(C=CC=C6)N=C5[H])=O)C(N[[email protected]@H](C)C4=O)=O)=O)=O)=O)=O)=O)C=CC=C2
Purity	≥98.0%

Storage & Handling

Shipping	Room temperature in continental US. May vary elsewhere.
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
Regulatory Status	This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use.