EDP-305

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Cat. No.: IBDI-434751

EDP-305 is an orally active, potent and selective farnesoid X receptor (FXR) agonist, with EC50 values of 34 nM (chimeric FXR in CHO cells) and 8 nM (full-length FXR in HEK cells). EDP-305 shows a potent and consistent antifibrotic effect. EDP-305 can be used for primary biliary cholangitis (PBC) and non-alcoholic steatohepatitis (NASH) research.

Size (Solution): 10 mM * 1 mL in DMSO

Size (Solid + Solvent): 10 mM * 1 mL ready for reconstitution

Size (Solid):

Product Details

Target	FXR \| Phosphatase \| Cytochrome P450
Molecular Weight	630.92
Appearance	Solid
SMILES	O[[email protected]]1[[email protected]]2([H])[[email protected]@](CC[[email protected]]3([[email protected]@]2([H])CC[[email protected]]3([H])[[email protected]](C)CCNC(NS(=O)(C4=CC=C(C=C4)C(C)(C)C)=O)=O)C)([H])[[email protected]@]5([[email protected]](C[[email protected]@H](CC5)O)([H])[[email protected]]1CC)C
Purity	96.01%

Storage & Handling

Shipping	Room temperature in continental US. May vary elsewhere.
Storage	Powder: -20°C/3 years; 4°C/2 years In solvent: -80°C/6 months; -20°C/1 month
Regulatory Status	This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use.

! For research use only, not intended for any clinical use.