EGFR/BRAF-IN-1

Cat. No.: IBDI-433337

EGFR/BRAF-IN-1 (compound 21), a 2,3-dihydropyrazino[1,2-a]indole-1,4-dione derivative, is a potent EGFR/BRAF inhibitor with an IC50 of 45 nM for BRAF V600E. EGFR/BRAF-IN-1 inhibits cancer cell proliferation (GI50=35 nM). EGFR/BRAF-IN-1 shows good antioxidant activity.

Product Details

Target	EGFR | Raf
Molecular Weight	481.97
SMILES	CCOCC1=C2C(N(CC(N2C3=CC=C(C=C31)Cl)=O)CCC4=CC=C(C=C4)N5CCOCC5)=O

Storage & Handling

Shipping	Room temperature in continental US. May vary elsewhere.
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
Regulatory Status	This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use.