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EIF2α activator 1

Cat. No.: IBDI-434230

EIF2α activator 1 (Compound 40) is an activator of eukaryotic initiation factor 2 alpha (eIF2α) phosphorylation. EIF2α activator 1 increases the expression level of eIF2α downstream proteins, ATF and CHOP. EIF2α activator 1 exhibits antiproliferative activity againist K562 and PBMC cells with IC50s of 4.00 and 19.3 μM, respectively.

Size (Solid):

Product Details

Target Eukaryotic Initiation Factor (eIF)
Molecular Weight 523.43
Appearance Solid
SMILES N#CC1=CC(C(F)(F)F)=CC(NC2=C(C(C2=O)=O)N[[email protected]@H]3CC[[email protected]@H](OC4=CC=C(C=C4)C(F)(F)F)CC3)=C1
Purity 98.77%

Storage & Handling

Shipping Room temperature in continental US. May vary elsewhere.
Storage Powder: -20°C/3 years; 4°C/2 years
In solvent: -80°C/6 months; -20°C/1 month
Regulatory Status This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use.
! For research use only, not intended for any clinical use.
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