eIF4A3-IN-12

Cat. No.: IBDI-433847

eIF4A3-IN-12 (compound 62) is a silvestrol (HY-13251) analogue. eIF4A3-IN-12 interferes the assembling of eIF4F translation complex with EC50s of 4, 70 and 5 nM for myc-LUC, tub-LUC and the growth inhibition for MBA-MB-231 cells. eIF4A3-IN-12 can be used for the research of human cancer pathogenesis.

Product Details

Target	Eukaryotic Initiation Factor (eIF)
Molecular Weight	496.94
Appearance	Solid
SMILES	COC1=CC=C([[email protected]@]23OC4=CC(Cl)=CC(OC)=C4[[email protected]]2(O)[[email protected]@H]([[email protected]@H]([[email protected]]3C5=CC=CC=C5)C(OC)=O)O)C=C1
Purity	99.70%

Storage & Handling

Shipping	Room temperature in continental US. May vary elsewhere.
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
Regulatory Status	This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use.