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eIF4A3-IN-9

Cat. No.: IBDI-434752

eIF4A3-IN-9 (compound 57) is a silvestrol (HY-13251) analogue. eIF4A3-IN-9 interferes the assembling of eIF4F translation complex with EC50s of 29, 450 and 80 nM for myc-LUC, tub-LUC and the growth inhibition for MBA-MB-231 cells. eIF4A3-IN-9 can be used for the research of human cancer pathogenesis.

Size (Solid):

Product Details

Target Eukaryotic Initiation Factor (eIF)
Molecular Weight 505.52
Appearance Solid
SMILES O[[email protected]]12[[email protected]](OC3=CC(C(N)=O)=CC(OC)=C32)(C4=CC=C(C=C4)OC)[[email protected]](C5=CC=CC=C5)[[email protected]]([[email protected]]1O)C(OC)=O

Storage & Handling

Shipping Room temperature in continental US. May vary elsewhere.
Storage Please store the product under the recommended conditions in the Certificate of Analysis.
Regulatory Status This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use.
! For research use only, not intended for any clinical use.