EMA/MUC1 Monoclonal Antibody

Target Information

Target Name	EMA/MUC1
Synonyms	MUC1 | CA15-3 | CD227 | Carcinoma-associated mucin | CD227 antigen | DF3 antigen | Episialin | Epithelial membrane antigen | H23 antigen | H23AG | Krebs von den Lungen-6 | MAM6 | MUC1/ZD | MUC-1/SEC | Mucin-1 | Pem | KL-6 | MUC-1/X | Tumor-associated mucin | Peanut-reactive urinary mucin | Polymorphic epithelial mucin | PUM | EMA | MUC-1 | Mucin 1, transmembrane
Uniprot ID	P15941
Immunogen	Recombinant full-length human MUC1 protein. Antigen Molecular Weight: 265-400 kDa.

Product Details

Description	Mouse monoclonal antibody to EMA/MUC1.
Host Species	Mouse
Clonality	Monoclonal
Purity	Protein A/G purified
Conjugation	Unconjugated
Modifications	Unmodified. Also available Azide-free, Carrier-free.
Reactivity	Human
Specificity	This MAb reacts with MUC1, a large transmembrane glycoprotein expressed on the ductal surface of normal glandular epithelia. The dominant epitope of this MAb involves both amino acids as well as sugar moieties. Neuraminidase treatment destroys the antigen. It is a very good tracer agent in CA15.3 assays. The extracellular domain of MUC1 largely consists of a highly conserved, O-glycosylated 20 amino acids tandem repeat which can occur 30-100 times per molecule depending on the length of the allele involved. In the vast majority of human carcinomas this protein is up-regulated and poorly glycosylated and appears on the cell surface in a non-polarized fashion.
Immunogen	Recombinant full-length human MUC1 protein. Antigen Molecular Weight: 265-400 kDa.
Application	IHC-P

Storage & Handling

Shipping	Shipped at 4 °C.
Storage	Store at 4 °C
Storage Buffer	10 mM PBS, 0.05% BSA, 0.05% Sodium Azide