EMA/MUC1 Monoclonal Antibody

Target Information

Target Name	EMA/MUC1
Synonyms	MUC1 | CA15-3 | CD227 | Carcinoma-associated mucin | CD227 antigen | DF3 antigen | Episialin | Epithelial membrane antigen | H23 antigen | H23AG | Krebs von den Lungen-6 | MAM6 | MUC1/ZD | MUC-1/SEC | Mucin-1 | Pem | KL-6 | MUC-1/X | Tumor-associated mucin | Peanut-reactive urinary mucin | Polymorphic epithelial mucin | PUM | EMA | MUC-1 | Mucin 1, transmembrane
Uniprot ID	P15941
Immunogen	Human milk fat globulin membrane preparation.

Product Details

Description	MUC1 antibody is an unconjugated mouse monoclonal antibody to human MUC1 (EMA).
Host Species	Mouse
Clonality	Monoclonal
Purity	Purified
Conjugation	Unconjugated
Modifications	Concentrated
Reactivity	Human
Specificity	The Human Mucin-1 antibody (BC-2) is reactive with 90% of breast carcinomas, most epithelial ovarian carcinomas and a high portion of lung, urogenital and gastrointestinal carcinomas. Some reactivity is observed in the apical membrane of normal breast epithelium. Weak reactivity is also present in pancreas, kidney and lung. This monoclonal reacts with a 5 amino acid epitope of the MUC-1 core protein which is less affective for glycosylation than the epitopes detected by other MUC-1 antibodies. Since BC-2 shows an excellent reactivity on paraffin embedded material and is reactive with a stable epitope this monoclonal is an important marker in routine histopathology.
Immunogen	Human milk fat globulin membrane preparation.
Application	IHC, IHC-Fr, IHC-P

Storage & Handling

Shipping	Shipped at 4 °C.
Storage	Store at 4 °C
Storage Buffer	PBS, 0.02% Sodium Azide, 0.1% BSA