EMA/MUC1 Monoclonal Antibody

Target Information

Target Name	EMA/MUC1
Synonyms	MUC1 | CA15-3 | CD227 | Carcinoma-associated mucin | CD227 antigen | DF3 antigen | Episialin | Epithelial membrane antigen | H23 antigen | H23AG | Krebs von den Lungen-6 | MAM6 | MUC1/ZD | MUC-1/SEC | Mucin-1 | Pem | KL-6 | MUC-1/X | Tumor-associated mucin | Peanut-reactive urinary mucin | Polymorphic epithelial mucin | PUM | EMA | MUC-1 | Mucin 1, transmembrane
Uniprot ID	P15941
Immunogen	High molecular weight (~300kD) glycoprotein from human milk-fat globule molecule.

Product Details

Description	MUC1 antibody is an unconjugated mouse monoclonal antibody to human MUC1 (EMA).
Host Species	Mouse
Clonality	Monoclonal
Purity	Protein A purified
Conjugation	Unconjugated
Modifications	Unmodified
Reactivity	Human
Specificity	Binds with high efficiency with a region of GVTSAPDTRPAPGSTAPPAHGVTSA synthetic peptide spanning the one repeat of VNTR extracellular portion of MUC1 molecule. Reacts with VNTR5 and VNTR20 recombinant unglycosylated fragments of MUC1 protein and underglycosylated MUC1 prepared from tumor fluids or as a result of chemical treatment of human milk MUC1. Does not recognize natural MUC1 protein isolated from human milk by affinity purification on carbohydrate epitope specific monoclonals and belongs to Monoclonal Cluster 1-4 according to ISOMB TD-4 classification. Does not cross-react with egg white avidin.
Immunogen	High molecular weight (~300kD) glycoprotein from human milk-fat globule molecule.
Application	IHC

Storage & Handling

Shipping	Shipped at 4 °C.
Storage	Short term: 4 °C. Long term: -20 °C
Storage Buffer	PBS, pH 7.4, 0.1% Sodium Azide
Handling	Avoid freeze-thaw cycles.