Embelin
Cat. No.: IBDI-430923
Embelin (Embelic acid), a potent, nonpeptidic XIAP; inhibitor (IC50=4.1 μM), inhibits cell growth, induces apoptosis, and activates caspase-9 in prostate cancer cells with high levels of XIAP; . Embelin blocks NF-kappaB signaling pathway leading to suppression of NF-kappaB-regulated antIAP; optotic and metastatic gene products. Embelin also induces autophagic and apoptotic cell death in human oral squamous cell carcinoma cells.
Size (Solid + Solvent): 10 mM * 1 mL ready for reconstitution
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Product Details
| Target |
IAP | NF-κB | Apoptosis | Autophagy |
| Molecular Weight |
294.39 |
| Appearance |
Solid |
| Synonyms |
Embelic acid, Emberine, NSC 91874 |
| SMILES |
O=C1C(O)=C(CCCCCCCCCCC)C(C(O)=C1)=O |
| Structure Classification |
Quinones>Benzene Quinones |
| Purity |
98.75% |
Storage & Handling
| Shipping |
Room temperature in continental US. May vary elsewhere. |
| Storage |
Please store the product under the recommended conditions in the Certificate of Analysis. |
| Regulatory Status |
This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. |
! For research use only, not intended for any clinical use.
