ENMD-1198

Cat. No.: IBDI-432297

ENMD-1198 (IRC-110160), an orally active microtubule destabilizing agent, is a 2-methoxyestradiol analogue with antiproliferative and antiangiogenic activity. ENMD-1198 is suitable for inhibiting HIF-1alpha and STAT3 in human HCC cells and leads to reduced tumor growth and vascularization.

Product Details

Target	Microtubule/Tubulin | HIF/HIF Prolyl-Hydroxylase | STAT
Molecular Weight	311.42
Appearance	Solid
Synonyms	IRC-110160
SMILES	C[[email protected]@]12C=CC[[email protected]@]1([H])[[email protected]]3([H])CCC4=C(C=C(OC)C(C(N)=O)=C4)[[email protected]@]3([H])CC2

Storage & Handling

Shipping	Room temperature in continental US. May vary elsewhere.
Storage	Powder: -20°C/3 years; 4°C/2 years In solvent: -80°C/6 months; -20°C/1 month
Regulatory Status	This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use.