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EPHA2/EPH Receptor A2 Monoclonal Antibody

Cat. No.: IBDA-430616

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Target Information

Target Name EPHA2/EPH Receptor A2
Synonyms EPHA2 | CTPA | EPH receptor A2 | Ephrin type-A receptor 2 | Epithelial cell kinase | ECK | Sek-2 | ARCC2 | Soluble EPHA2 variant 1 | CTPP1
Uniprot ID P29317
Immunogen 1C1 was isolated after screening of a non-immunized human Fab phage library. Selection was based on the ability to bind soluble human recombinant EphA2 (aa 183-510). The Fab was subsequently converted to full length human IgG1.

Product Details

Description This EPHA2 / EPH Receptor A2 antibody is an unconjugated Rabbit/Human chimeric recombinant monoclonal antibody.
Host Species Rabbit
Clonality Monoclonal
Purity Protein A purified
Conjugation Unconjugated
Modifications Unmodified
Reactivity Human
Specificity 1C1 binds specifically to the amino-termianal LBD (ligand-binding domain) region of the EphA2 ectodomain (IgG1 KD ~0.8 nM; Fab KD ~140 nM) and not to other related human Eph receptors such as EphA1, EphA2, and EphA4, or any EphB receptor family members.
Immunogen 1C1 was isolated after screening of a non-immunized human Fab phage library. Selection was based on the ability to bind soluble human recombinant EphA2 (aa 183-510). The Fab was subsequently converted to full length human IgG1.
Application Agon, ELISA, Flo, IF, WB

Storage & Handling

Shipping Shipped at 4 °C.
Storage Short term: 4 °C. Long term: -20 °C
Storage Buffer PBS, 0.02% ProClin 300.
Handling Avoid freeze-thaw cycles.
! For research use only, not intended for any clinical use.