Cat. No.: IBDA-430617
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Online InquiryTarget Information
| Target Name | EPHA2/EPH Receptor A2 |
| Synonyms | EPHA2 | CTPA | EPH receptor A2 | Ephrin type-A receptor 2 | Epithelial cell kinase | ECK | Sek-2 | ARCC2 | Soluble EPHA2 variant 1 | CTPP1 |
| Uniprot ID | P29317 |
| Immunogen | 1C1 was isolated after screening of a non-immunized human Fab phage library. Selection was based on the ability to bind soluble human recombinant EphA2 (aa 183-510). The Fab was subsequently converted to full length human IgG1. |
Product Details
| Description | This EPHA2 / EPH Receptor A2 antibody is an unconjugated Human/Human chimeric recombinant monoclonal antibody. |
| Host Species | Human |
| Clonality | Monoclonal |
| Purity | Protein A purified |
| Conjugation | Unconjugated |
| Modifications | Unmodified |
| Reactivity | Human |
| Specificity | 1C1 binds specifically to the amino-termianal LBD (ligand-binding domain) region of the EphA2 ectodomain (IgG1 KD ~0.8 nM; Fab KD ~140 nM) and not to other related human Eph receptors such as EphA1, EphA2, and EphA4, or any EphB receptor family members. |
| Immunogen | 1C1 was isolated after screening of a non-immunized human Fab phage library. Selection was based on the ability to bind soluble human recombinant EphA2 (aa 183-510). The Fab was subsequently converted to full length human IgG1. |
| Application | Agon, ELISA, Flo, IF, WB |
Storage & Handling
| Shipping | Shipped at 4 °C. |
| Storage | Short term: 4 °C. Long term: -20 °C |
| Storage Buffer | PBS, 0.02% ProClin 300. |
| Handling | Avoid freeze-thaw cycles. |