ERα degrader 4

Cat. No.: IBDI-431884

ERα degrader 4 is an excellent and selective estrogen receptor α (ERα) degrader (IC50 of 0.31, 0.41 and 0.48 μM in MDA-MB-231, MCF-7 and MCF-7/ADR cells, respectively). ERα degrader 4 has potent inhibitory activity against MCF-7 cell lines. ERα degrader 4 is a potential SERDs candidate for the research of breast cancer.

Product Details

Target	Estrogen Receptor/ERR | Apoptosis
Molecular Weight	690.91
SMILES	[H][[email protected]]12C[[email protected]]3(CC[[email protected]]([[email protected]](/C=C\C=C/C(OCCOCCOCCOC(CC45CC6CC(C5)CC(C6)C4)=O)=O)C)([[email protected]@]3(C/C=C([[email protected]@]1(C(C=C2C)=O)[H])/C=O)[H])[H])C

Storage & Handling

Shipping	Room temperature in continental US. May vary elsewhere.
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
Regulatory Status	This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use.