Ethacrynic acid sodium

Cat. No.: IBDI-436791

Ethacrynic acid (Etacrynic acid sodium) sodium is a diuretic. Ethacrynic acid sodium is an inhibitor of glutathione S-transferases (GSTs). Ethacrynic acid sodium is a potent inhibitor of NF-kB-signaling pathway, and also modulates leukotriene formation. Ethacrynic acid sodium also inhibits L-type voltage-dependent and store-operated calcium channel, leading to relaxation of airway smooth muscle (ASM) cells. Ethacrynic acid sodium has anti-inflammatory properties that reduces the retinoid-induced ear edema in mice.

Product Details

Target	NF-κB | Gutathione S-TransfeRase | Calcium Channel
Molecular Weight	325.12
Synonyms	Etacrynic acid sodium, Sodium etacrynate
SMILES	O=C(O[Na])COC1=CC=C(C(C(CC)=C)=O)C(Cl)=C1Cl

Storage & Handling

Shipping	Room temperature in continental US. May vary elsewhere.
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
Regulatory Status	This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use.