Fas Polyclonal Antibody

Target Information

Target Name	Fas
Uniprot ID	P25445
Cellular Localization	Secreted and Cell membrane.
Immunogen	Recombinant fragment corresponding to Human Fas aa 1-200.
Function	Receptor for TNFSF6/FASLG. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. FAS-mediated apoptosis may have a role in the induction of peripheral tolerance, in the antigen-stimulated suicide of mature T-cells, or both. The secreted isoforms 2 to 6 block apoptosis (in vitro).

Product Details

Description	Biotin Rabbit polyclonal antibody to Fas.
Host Species	Rabbit
Clonality	Polyclonal
Purity	Affinity purified
Isotype	IgG
Conjugation	Biotin
Reactivity	Recombinant fragment
Immunogen	Recombinant fragment corresponding to Human Fas aa 1-200.
Application	sELISA, WB

Storage & Handling

Shipping	Shipped at 4 °C.
Storage	Store at -20ºC. Store in the dark
Storage Buffer	Constituent: PBS, 0.1% BSA
Handling	Avoid freeze-thaw cycles.