Fenbendazole
Cat. No.: IBDI-436837
Fenbendazole is an orally active benzimidazole anthelmintic agent, with a broad antiparasitic range. Fenbendazole is a microtubule destabilizing agent and acts on helminthes primarily by binding to tubulin and disrupting the tubulin microtubule equilibrium. Fenbendazole stabilizes the transcriptional activator HIF-1α. Fenbendazole possesses an efficient anti-proliferative activity and induces apoptosis. Fenbendazole causes cell-cycle arrest and mitotic cell death, and has antitumor activity in mice xenografted with wild-type p53.
Size (Solid + Solvent): 10 mM * 1 mL ready for reconstitution
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Product Details
Target |
PaRasite | HIF/HIF Prolyl-Hydroxylase | Microtubule/Tubulin | Antibiotic |
Molecular Weight |
299.35 |
Appearance |
Solid |
SMILES |
O=C(OC)NC1=NC2=CC=C(SC3=CC=CC=C3)C=C2N1 |
Purity |
99.84% |
Storage & Handling
Shipping |
Room temperature in continental US. May vary elsewhere. |
Storage |
Powder: -20°C/3 years; 4°C/2 years In solvent: -80°C/6 months; -20°C/1 month |
Regulatory Status |
This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. |
! For research use only, not intended for any clinical use.