Cat. No.: IBDA-433454
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Online InquiryTarget Information
| Target Name | FLAP |
| Uniprot ID | P20292 |
| Cellular Localization | Nucleus membrane. Endoplasmic reticulum membrane. |
| Immunogen | Synthetic peptide within Human FLAP aa 100-200. |
| Function | Required for leukotriene biosynthesis by ALOX5 (5-lipoxygenase). Anchors ALOX5 to the membrane. Binds arachidonic acid, and could play an essential role in the transfer of arachidonic acid to ALOX5. Binds to MK-886, a compound that blocks the biosynthesis of leukotrienes. |
Product Details
| Description | Rabbit monoclonal antibody to FLAP. |
| Host Species | Rabbit |
| Clonality | Monoclonal |
| Purity | Protein A purified |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Reactivity | Human |
| Immunogen | Synthetic peptide within Human FLAP aa 100-200. |
| Positive Control | Raji, THP-1, HepG2, and K562 cell lysates |
| Application | WB |
Storage & Handling
| Shipping | Shipped at 4 °C. |
| Storage | Upon delivery aliquot. Store at -20 °C |
| Storage Buffer | pH: 7.20 Preservative: 0.05% Sodium Azide Constituent: 40% Glycerol, 9.85% Tris Glycine, 50% Tissue Culture Supernatant |
| Handling | Avoid freeze-thaw cycles. |